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Quick Details

  • CAS No.: 53003-10-4
  • Other Names: (2R)-2-((5S)-6-{5-[(10S,12R)-2-((6S,5R)-5-Ethyl
  • MF: C42H70O11
  • EINECS No.: 258-290-1
  • Place of Origin: Shaanxi, China (Mainland)
  • Type: Antibiotic and Antimicrobial Agents
  • Grade Standard: Medicine Grade
  • Brand Name: SHUNYI
  • Model Number: usp
  • Purity: 12% 24%
  • color: off white

Packaging & Delivery

Packaging Details: 25kg/drum
Delivery Detail: promptly

1.Form: granular
2.Content: Salinomycin sodium 12%, 24%
3.Packing: 25kgs/bag
4.GMP & ISO
4.Function: polyether antibiotic

Salinomycin is a polyether antibiotic from the group of ionophores. It exerts anticoccidial effect against all species known as causative agents of coccidiosis in poultry (Eimeria acervulina, E. maxima, E. necatrix, E. mivati, E. tenella, E. brunetti) as well as in the other farm animals (E. meleagridis, E. meleagrimitis, E. bovis, etc.). It is active against Gram-positive microorganisms, some anaerobes and Serpulina (Treponema) hyodysenteriae. The biological activity of salinomycin is based on its ability to form lipophilic complexes with the monovalent alkaline ions, making the cellular membranes of coccidia permeable to the ions mentioned. In this way, the intracellular ion concentration in the parasite cells is disturbed and anticoccidial effect of the preparation is achieved. This action is manifested already at the earliest stage of coccidia development hindering the maturity of the schizonts and the development of merozoites. An additional influence is the impeded transport of carbohydrate and the active sporozoite glycolysis provoked by salinomycin. The administration of salinomycin with the feed to ruminants (with developed forestomachs) at the recommended concentrations improves the weight gain and the feed conversion efficiency of the animals (as a result of the influence on the microflora and microfauna in the forestomachs which leads to an increase in the concentration of propionic acid and a decrease in the concentrations of lactic acid and acetic acid and a diminution of methane eructation from the rumen). Salinomycin reveals a nutritive effect in the growing and fattening pigs as well (affecting positively the beneficial microflora in the digestive tract of the animals).

 

COMPOSITION

 

Salinopharm 12% premix

Salinomycin sodium

12 g

Excipients

up to 100 g

 

 

 

Product name

Salinomycin Premix 12%

Items

Specification

Appearance

yellow-brownish granules

Identification

Ethanol solution of the substance to be examined reacting with vanillin test solution shows red

Particle size

≥95% pass through a 24 mesh sieve

Loss on drying

≤8.0%

Heavy metals

≤0.0020%

Arsenic

≤0.0002%

Salinomycin A

>85.0%

Related impurity fill

peak area of single impurity ≤5.0%

 

peak area of total impurities ≤10.0%

Assay

Content of labeled amount 90.0%%~110.0%

 

Potency 120u/mg

Packing

25kg/bag

 

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